Cargando…

A surgical method for continuous intraportal infusion of gut microbial metabolites in mice

Gut microbe–derived metabolites influence human physiology and disease. However, establishing mechanistic links between gut microbial metabolites and disease pathogenesis in animal models remains challenging. The major route of absorption for microbe-derived small molecules is venous drainage via th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Orabi, Danny, Osborn, Lucas J., Fung, Kevin, Massey, William, Horak, Anthony J., Aucejo, Federico, Choucair, Ibrahim, DeLucia, Beckey, Wang, Zeneng, Claesen, Jan, Brown, J. Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2021
Materias:	Technical Advance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262340/ https://www.ncbi.nlm.nih.gov/pubmed/33986195 http://dx.doi.org/10.1172/jci.insight.145607

Ejemplares similares

A gut microbial metabolite of dietary polyphenols reverses obesity-driven hepatic steatosis
por: Osborn, Lucas J., et al.
Publicado: (2022)

Positron Emission Tomography to Assess the Outcome of Intraportal Islet Transplantation
por: Eriksson, Olof, et al.
Publicado: (2016)

Flavin-Containing Monooxygenase 3 (FMO3) Is Critical for Dioxin-Induced Reorganization of the Gut Microbiome and Host Insulin Sensitivity
por: Massey, William, et al.
Publicado: (2022)

Identification of microbial DNA in human cancer
por: Duncan, Christopher G, et al.
Publicado: (2009)

Metabolite profiling of non‐sterile rhizosphere soil
por: Pétriacq, Pierre, et al.
Publicado: (2017)

New generation continuous cardiac output monitoring from carbon dioxide elimination
por: Peyton, Philip J., et al.
Publicado: (2019)

Computer-controlled closed-loop drug infusion system for automated hemodynamic resuscitation in endotoxin-induced shock
por: Uemura, Kazunori, et al.
Publicado: (2017)

Metabolite annotations based on the integration of mass spectral information
por: Iijima, Yoko, et al.
Publicado: (2008)

How to design a dose-finding study using the continual reassessment method
por: Wheeler, Graham M., et al.
Publicado: (2019)

A 3D‐printable device allowing fast and reproducible longitudinal preparation of mouse intestines
por: DeLucia, Beckey, et al.
Publicado: (2022)

A machine-independent method to have active removal of 5,000 centistokes silicone oil using plastic infusion tube and 23-gauge microcannulas
por: Zhang, Zhaotian, et al.
Publicado: (2015)

MS/MS spectral tag-based annotation of non-targeted profile of plant secondary metabolites
por: Matsuda, Fumio, et al.
Publicado: (2009)

COSORE: A community database for continuous soil respiration and other soil‐atmosphere greenhouse gas flux data
por: Bond‐Lamberty, Ben, et al.
Publicado: (2020)

Preventing clinically relevant pancreatic fistula with combination of linear stapling plus continuous suture of the stump in laparoscopic distal pancreatectomy
por: Aoki, Takeshi, et al.
Publicado: (2020)

A case study: a continuous improvement project of lecturing skills for clinical teachers in Chinese residency standardized training
por: Sun, Xiaoliang, et al.
Publicado: (2022)

Detection of bacterial pathogens from clinical specimens using conventional microbial culture and 16S metagenomics: a comparative study
por: Abayasekara, Lalanika M., et al.
Publicado: (2017)

Quantifying microbial growth and carbon use efficiency in dry soil environments via (18)O water vapor equilibration
por: Canarini, Alberto, et al.
Publicado: (2020)

Liver Glycogen Loading Dampens Glycogen Synthesis Seen in Response to Either Hyperinsulinemia or Intraportal Glucose Infusion
por: Winnick, Jason J., et al.
Publicado: (2013)

Use of real time continuous glucose monitoring and intravenous insulin in type 1 diabetic mothers to prevent respiratory distress and hypoglycaemia in infants
por: Iafusco, Dario, et al.
Publicado: (2008)

Double-plating of ovine critical sized defects of the tibia: a low morbidity model enabling continuous in vivo monitoring of bone healing
por: Hahn, Joachim A, et al.
Publicado: (2011)

A novel approach to determine two optimal cut-points of a continuous predictor with a U-shaped relationship to hazard ratio in survival data: simulation and application
por: Chen, Yimin, et al.
Publicado: (2019)

Practicalities in running early-phase trials using the time-to-event continual reassessment method (TiTE-CRM) for interventions with long toxicity periods using two radiotherapy oncology trials as examples
por: van Werkhoven, Erik, et al.
Publicado: (2020)

Tissue metabolites in diffuse glioma and their modulations by IDH1 mutation, histology, and treatment
por: Trautwein, Christoph, et al.
Publicado: (2022)

A network of immune and microbial modifications underlies viral persistence in the gastrointestinal tract
por: Macleod, Bethany L., et al.
Publicado: (2020)

Magnetic resonance imaging of cerebrospinal fluid outflow after low-rate lateral ventricle infusion in mice
por: Decker, Yann, et al.
Publicado: (2022)

Oxygenation of the Intraportally Transplanted Pancreatic Islet
por: Suszynski, Thomas M., et al.
Publicado: (2016)

Extracting multiple interacting root systems using X‐ray microcomputed tomography
por: Mairhofer, Stefan, et al.
Publicado: (2015)

Attaching metabolic expenditures to standard occupational classification systems: perspectives from time-use research
por: Deyaert, J., et al.
Publicado: (2017)

Prone during pandemic: development and implementation of a quality-based protocol for proning severe COVID-19 hypoxic lung failure patients in situationally or historically low resource hospitals
por: Astua, Alfredo J., et al.
Publicado: (2021)

Assessing risk of bias: a proposal for a unified framework for observational studies and randomized trials
por: Luijendijk, Hendrika J., et al.
Publicado: (2020)

Establishing a robust multidisciplinary team process in complex abdominal wall reconstruction within a colorectal surgical unit
por: Muirhead, L. J., et al.
Publicado: (2019)

New surgical approach for late complications from spinal cord injury
por: Reis, Antonio J
Publicado: (2006)

Subcutaneous dissociative conscious sedation (sDCS) an alternative method for airway regional blocks: a new approach
por: Javid, Mihan J
Publicado: (2011)

A tool for sharing annotated research data: the "Category 0" UMLS (Unified Medical Language System) vocabularies
por: Berman, Jules J
Publicado: (2003)

Expression-based Pathway Signature Analysis (EPSA): Mining publicly available microarray data for insight into human disease
por: Tenenbaum, Jessica D, et al.
Publicado: (2008)

A novel mechanical lung model of pulmonary diseases to assist with teaching and training
por: Chase, J Geoffrey, et al.
Publicado: (2006)

Ear biometrics for patient identification in global health: a field study to test the effectiveness of an image stabilization device in improving identification accuracy
por: Etter, Lauren P., et al.
Publicado: (2019)

Reliability of accelerometric assessment of balance in children aged 6–12 years
por: García-Liñeira, J., et al.
Publicado: (2020)

Evidence and Value: Impact on DEcisionMaking – the EVIDEM framework and potential applications
por: Goetghebeur, Mireille M, et al.
Publicado: (2008)

Development of a posterior sagittal anorectal surgical teaching model
por: van Ling, J. A., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ui3rliin0vf8tggg2ovfhfuckk