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lncRNA DRAIR is downregulated in diabetic monocytes and modulates the inflammatory phenotype via epigenetic mechanisms

Long noncoding RNAs (lncRNAs) are increasingly implicated in the pathology of diabetic complications. Here, we examined the role of lncRNAs in monocyte dysfunction and inflammation associated with human type 2 diabetes mellitus (T2D). RNA sequencing analysis of CD14(+) monocytes from patients with T...

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Detalles Bibliográficos
Autores principales: Reddy, Marpadga A., Amaram, Vishnu, Das, Sadhan, Tanwar, Vinay Singh, Ganguly, Rituparna, Wang, Mei, Lanting, Linda, Zhang, Lingxiao, Abdollahi, Maryam, Chen, Zhuo, Wu, Xiwei, Devaraj, Sridevi, Natarajan, Rama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262346/
https://www.ncbi.nlm.nih.gov/pubmed/33945509
http://dx.doi.org/10.1172/jci.insight.143289