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lncRNA DRAIR is downregulated in diabetic monocytes and modulates the inflammatory phenotype via epigenetic mechanisms
Long noncoding RNAs (lncRNAs) are increasingly implicated in the pathology of diabetic complications. Here, we examined the role of lncRNAs in monocyte dysfunction and inflammation associated with human type 2 diabetes mellitus (T2D). RNA sequencing analysis of CD14(+) monocytes from patients with T...
Autores principales: | Reddy, Marpadga A., Amaram, Vishnu, Das, Sadhan, Tanwar, Vinay Singh, Ganguly, Rituparna, Wang, Mei, Lanting, Linda, Zhang, Lingxiao, Abdollahi, Maryam, Chen, Zhuo, Wu, Xiwei, Devaraj, Sridevi, Natarajan, Rama |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262346/ https://www.ncbi.nlm.nih.gov/pubmed/33945509 http://dx.doi.org/10.1172/jci.insight.143289 |
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