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In vitro model of ischemic heart failure using human induced pluripotent stem cell–derived cardiomyocytes

Human induced pluripotent stem cell–derived cardiomyocytes (hiPSC-CMs) have been used extensively to model inherited heart diseases, but hiPSC-CM models of ischemic heart disease are lacking. Here, our objective was to generate an hiPSC-CM model of ischemic heart disease. To this end, hiPSCs were di...

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Detalles Bibliográficos
Autores principales: Davis, Justin, Chouman, Ahmad, Creech, Jeffery, Monteiro da Rocha, Andre, Ponce-Balbuena, Daniela, Jimenez Vazquez, Eric N., Nichols, Ruthann, Lozhkin, Andrey, Madamanchi, Nageswara R., Campbell, Katherine F., Herron, Todd J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262347/
https://www.ncbi.nlm.nih.gov/pubmed/33878037
http://dx.doi.org/10.1172/jci.insight.134368