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Hypoxia acts as an environmental cue for the human tissue-resident memory T cell differentiation program
Tissue-resident memory T cells (T(RM)) provide frontline defense against infectious diseases and contribute to antitumor immunity; however, aside from the necessity of TGF-β, knowledge regarding T(RM)-inductive cues remains incomplete, particularly for human cells. Oxygen tension is an environmental...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262358/ https://www.ncbi.nlm.nih.gov/pubmed/34027895 http://dx.doi.org/10.1172/jci.insight.138970 |