MMP2 and TLRs modulate immune responses in the tumor microenvironment

The presence of an immunosuppressive tumor microenvironment is a major obstacle in the success of cancer immunotherapies. Because extracellular matrix components can shape the microenvironment, we investigated the role of matrix metalloproteinase 2 (MMP2) in melanoma tumorigenesis. We found that MMP...

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Detalles Bibliográficos
Autores principales: Muniz-Bongers, Luciana R., McClain, Christopher B., Saxena, Mansi, Bongers, Gerold, Merad, Miriam, Bhardwaj, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262464/
https://www.ncbi.nlm.nih.gov/pubmed/34032639
http://dx.doi.org/10.1172/jci.insight.144913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262464/
https://www.ncbi.nlm.nih.gov/pubmed/34032639
http://dx.doi.org/10.1172/jci.insight.144913

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