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Single-cell profiling identifies impaired adaptive NK cells expanded after HCMV reactivation in haploidentical HSCT

Haploidentical hematopoietic stem cell transplantation (h-HSCT) represents an efficient curative approach for patients affected by hematologic malignancies in which the reduced intensity conditioning induces a state of immunologic tolerance between donor and recipient. However, opportunistic viral i...

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Detalles Bibliográficos
Autores principales: Zaghi, Elisa, Calvi, Michela, Puccio, Simone, Spata, Gianmarco, Terzoli, Sara, Peano, Clelia, Roberto, Alessandra, De Paoli, Federica, van Beek, Jasper J.P., Mariotti, Jacopo, De Philippis, Chiara, Sarina, Barbara, Mineri, Rossana, Bramanti, Stefania, Santoro, Armando, Le-Trilling, Vu Thuy Khanh, Trilling, Mirko, Marcenaro, Emanuela, Castagna, Luca, Di Vito, Clara, Lugli, Enrico, Mavilio, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262468/
https://www.ncbi.nlm.nih.gov/pubmed/34003794
http://dx.doi.org/10.1172/jci.insight.146973