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Gut germinal center regeneration and enhanced antiviral immunity by mesenchymal stem/stromal cells in SIV infection

Although antiretroviral therapy suppresses HIV replication, it does not eliminate viral reservoirs or restore damaged lymphoid tissue, posing obstacles to HIV eradication. Using the SIV model of AIDS, we investigated the effect of mesenchymal stem/stromal cell (MSC) infusions on gut mucosal recovery...

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Detalles Bibliográficos
Autores principales: Weber, Mariana G., Walters-Laird, Chara J., Kol, Amir, Santos Rocha, Clarissa, Hirao, Lauren A., Mende, Abigail, Balan, Bipin, Arredondo, Juan, Elizaldi, Sonny R., Iyer, Smita S., Tarantal, Alice F., Dandekar, Satya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262475/
https://www.ncbi.nlm.nih.gov/pubmed/34014838
http://dx.doi.org/10.1172/jci.insight.149033