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RIP3-dependent necroptosis contributes to the pathogenesis of chronic obstructive pulmonary disease

Necroptosis has emerged as a potential mechanism in the pathogenesis of chronic obstructive pulmonary disease (COPD). Here, we found that markers of necroptosis, including high mobility group box 1 release and phosphorylation of mixed lineage kinase domain-like protein (p-MLKL), were markedly induce...

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Detalles Bibliográficos
Autores principales: Chen, Dongshi, Gregory, Alyssa D., Li, Xiaoyun, Wei, Jianxin, Burton, Christine L., Gibson, Gregory, Scott, Stephen J., St. Croix, Claudette M., Zhang, Yingze, Shapiro, Steven D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262480/
https://www.ncbi.nlm.nih.gov/pubmed/34156033
http://dx.doi.org/10.1172/jci.insight.144689