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RIP3-dependent necroptosis contributes to the pathogenesis of chronic obstructive pulmonary disease
Necroptosis has emerged as a potential mechanism in the pathogenesis of chronic obstructive pulmonary disease (COPD). Here, we found that markers of necroptosis, including high mobility group box 1 release and phosphorylation of mixed lineage kinase domain-like protein (p-MLKL), were markedly induce...
Autores principales: | Chen, Dongshi, Gregory, Alyssa D., Li, Xiaoyun, Wei, Jianxin, Burton, Christine L., Gibson, Gregory, Scott, Stephen J., St. Croix, Claudette M., Zhang, Yingze, Shapiro, Steven D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262480/ https://www.ncbi.nlm.nih.gov/pubmed/34156033 http://dx.doi.org/10.1172/jci.insight.144689 |
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