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p38 MAPKs — roles in skeletal muscle physiology, disease mechanisms, and as potential therapeutic targets

p38 MAPKs play a central role in orchestrating the cellular response to stress and inflammation and in the regulation of myogenesis. Potent inhibitors of p38 MAPKs have been pursued as potential therapies for several disease indications due to their antiinflammatory properties, although none have be...

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Detalles Bibliográficos
Autores principales: Brennan, Christopher M., Emerson, Charles P., Owens, Jane, Christoforou, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262482/
https://www.ncbi.nlm.nih.gov/pubmed/34156029
http://dx.doi.org/10.1172/jci.insight.149915