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Incubation of Oxycodone Craving Following Adult-Onset and Adolescent-Onset Oxycodone Self-Administration in Male Rats

Relapse is a major obstacle to curb the ongoing epidemic of prescription opioid abuse. We and others previously demonstrated that oxycodone seeking in adult rats progressively increases after abstinence from oxycodone self-administration (incubation of oxycodone craving). In humans, the onset of oxy...

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Detalles Bibliográficos
Autores principales: Altshuler, Rachel D., Garcia, Kristine T., Li, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262493/
https://www.ncbi.nlm.nih.gov/pubmed/34248518
http://dx.doi.org/10.3389/fnbeh.2021.697509