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Molecular clock REV-ERBα regulates cigarette smoke–induced pulmonary inflammation and epithelial-mesenchymal transition

Cigarette smoke (CS) is the main etiological factor in the pathogenesis of emphysema/chronic obstructive pulmonary disease (COPD), which is associated with abnormal epithelial-mesenchymal transition (EMT). Previously, we have shown an association among circadian rhythms, CS-induced lung inflammation...

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Detalles Bibliográficos
Autores principales: Wang, Qixin, Sundar, Isaac K., Lucas, Joseph H., Muthumalage, Thivanka, Rahman, Irfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262497/
https://www.ncbi.nlm.nih.gov/pubmed/34014841
http://dx.doi.org/10.1172/jci.insight.145200