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Reaction of [(18)F]Fluoride at Heteroatoms and Metals for Imaging of Peptides and Proteins by Positron Emission Tomography

The ability to radiolabel proteins with [(18)F]fluoride enables the use of positron emission tomography (PET) for the early detection, staging and diagnosis of disease. The direct fluorination of native proteins through C-F bond formation is, however, a difficult task. The aqueous environments requi...

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Detalles Bibliográficos
Autores principales: Scroggie, Kymberley R., Perkins, Michael V., Chalker, Justin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262615/
https://www.ncbi.nlm.nih.gov/pubmed/34249861
http://dx.doi.org/10.3389/fchem.2021.687678