Preclinical evidence for the therapeutic value of TBX5 normalization in arrhythmia control

AIMS : Arrhythmias and sudden cardiac death (SCD) occur commonly in patients with heart failure. We found T-box 5 (TBX5) dysregulated in ventricular myocardium from heart failure patients and thus we hypothesized that TBX5 reduction contributes to arrhythmia development in these patients. To underst...

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Detalles Bibliográficos
Autores principales: Rathjens, Franziska S, Blenkle, Alica, Iyer, Lavanya M, Renger, Anke, Syeda, Fahima, Noack, Claudia, Jungmann, Andreas, Dewenter, Matthias, Toischer, Karl, El-Armouche, Ali, Müller, Oliver J, Fabritz, Larissa, Zimmermann, Wolfram-Hubertus, Zelarayan, Laura C, Zafeiriou, Maria-Patapia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262635/
https://www.ncbi.nlm.nih.gov/pubmed/32777030
http://dx.doi.org/10.1093/cvr/cvaa239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262635/
https://www.ncbi.nlm.nih.gov/pubmed/32777030
http://dx.doi.org/10.1093/cvr/cvaa239

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