Role and mechanism of chaperones calreticulin and ERP57 in restoring trafficking to mutant HERG-A561V protein

Long QT syndrome type 2 is caused by a mutation in the human-ether-a-go-go-related gene (HERG) gene encoding the rapidly activating delayed rectifier K-current. HERG is a key cell membrane glycoprotein; however, whether the maturation process of HERG protein involves key molecules derived from the c...

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Detalles Bibliográficos
Autores principales: Wu, Yujia, Huang, Xiaoyan, Zheng, Zequn, Yang, Xi, Ba, Yanna, Lian, Jiangfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262656/
https://www.ncbi.nlm.nih.gov/pubmed/34212985
http://dx.doi.org/10.3892/ijmm.2021.4992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262656/
https://www.ncbi.nlm.nih.gov/pubmed/34212985
http://dx.doi.org/10.3892/ijmm.2021.4992

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