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Role and mechanism of chaperones calreticulin and ERP57 in restoring trafficking to mutant HERG-A561V protein
Long QT syndrome type 2 is caused by a mutation in the human-ether-a-go-go-related gene (HERG) gene encoding the rapidly activating delayed rectifier K-current. HERG is a key cell membrane glycoprotein; however, whether the maturation process of HERG protein involves key molecules derived from the c...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262656/ https://www.ncbi.nlm.nih.gov/pubmed/34212985 http://dx.doi.org/10.3892/ijmm.2021.4992 |