Physiologically Based Pharmacokinetics Model in Pregnancy: A Regulatory Perspective on Model Evaluation

Physiologically based pharmacokinetics (PBPK) modelling is widely used in medicine development and regulatory submissions. The lack of clinical pharmacokinetic data in pregnancy is widely acknowledged; therefore, one area of current interest is in the use of PBPK modelling to describe the potential...

Descripción completa

Detalles Bibliográficos
Autores principales: Coppola, Paola, Kerwash, Essam, Cole, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262675/
https://www.ncbi.nlm.nih.gov/pubmed/34249817
http://dx.doi.org/10.3389/fped.2021.687978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262675/
https://www.ncbi.nlm.nih.gov/pubmed/34249817
http://dx.doi.org/10.3389/fped.2021.687978

Ejemplares similares