Mechanisms of PI(4,5)P2 Enrichment in HIV-1 Viral Membranes

Phosphatidylinositol 4,5-bisphosphate (PIP2) is critical for HIV-1 virus assembly. The viral membrane is enriched in PIP2, suggesting that the virus assembles at PIP2-rich microdomains. We showed previously that in model membranes PIP2 can form nanoscopic clusters bridged by multivalent cations. Her...

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Detalles Bibliográficos
Autores principales: Wen, Yi, Feigenson, Gerald W., Vogt, Volker M., Dick, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262684/
https://www.ncbi.nlm.nih.gov/pubmed/32739462
http://dx.doi.org/10.1016/j.jmb.2020.07.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262684/
https://www.ncbi.nlm.nih.gov/pubmed/32739462
http://dx.doi.org/10.1016/j.jmb.2020.07.018

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