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Mechanisms of PI(4,5)P2 Enrichment in HIV-1 Viral Membranes

Phosphatidylinositol 4,5-bisphosphate (PIP2) is critical for HIV-1 virus assembly. The viral membrane is enriched in PIP2, suggesting that the virus assembles at PIP2-rich microdomains. We showed previously that in model membranes PIP2 can form nanoscopic clusters bridged by multivalent cations. Her...

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Detalles Bibliográficos
Autores principales:	Wen, Yi, Feigenson, Gerald W., Vogt, Volker M., Dick, Robert A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262684/ https://www.ncbi.nlm.nih.gov/pubmed/32739462 http://dx.doi.org/10.1016/j.jmb.2020.07.018

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