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mmCSM-PPI: predicting the effects of multiple point mutations on protein–protein interactions
Protein–protein interactions play a crucial role in all cellular functions and biological processes and mutations leading to their disruption are enriched in many diseases. While a number of computational methods to assess the effects of variants on protein–protein binding affinity have been propose...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262703/ https://www.ncbi.nlm.nih.gov/pubmed/33893812 http://dx.doi.org/10.1093/nar/gkab273 |