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mmCSM-PPI: predicting the effects of multiple point mutations on protein–protein interactions

Protein–protein interactions play a crucial role in all cellular functions and biological processes and mutations leading to their disruption are enriched in many diseases. While a number of computational methods to assess the effects of variants on protein–protein binding affinity have been propose...

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Detalles Bibliográficos
Autores principales: Rodrigues, Carlos H M, Pires, Douglas E V, Ascher, David B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262703/
https://www.ncbi.nlm.nih.gov/pubmed/33893812
http://dx.doi.org/10.1093/nar/gkab273