Piezo1 channels restrain regulatory T cells but are dispensable for effector CD4(+) T cell responses

T lymphocytes encounter complex mechanical cues during an immune response. The mechanosensitive ion channel, Piezo1, drives inflammatory responses to bacterial infections, wound healing, and cancer; however, its role in helper T cell function remains unclear. In an animal model for multiple sclerosi...

Descripción completa

Detalles Bibliográficos
Autores principales: Jairaman, Amit, Othy, Shivashankar, Dynes, Joseph L., Yeromin, Andriy V., Zavala, Angel, Greenberg, Milton L., Nourse, Jamison L., Holt, Jesse R., Cahalan, Stuart M., Marangoni, Francesco, Parker, Ian, Pathak, Medha M., Cahalan, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262815/
https://www.ncbi.nlm.nih.gov/pubmed/34233878
http://dx.doi.org/10.1126/sciadv.abg5859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262815/
https://www.ncbi.nlm.nih.gov/pubmed/34233878
http://dx.doi.org/10.1126/sciadv.abg5859

Ejemplares similares