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Piezo1 channels restrain regulatory T cells but are dispensable for effector CD4(+) T cell responses
T lymphocytes encounter complex mechanical cues during an immune response. The mechanosensitive ion channel, Piezo1, drives inflammatory responses to bacterial infections, wound healing, and cancer; however, its role in helper T cell function remains unclear. In an animal model for multiple sclerosi...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262815/ https://www.ncbi.nlm.nih.gov/pubmed/34233878 http://dx.doi.org/10.1126/sciadv.abg5859 |