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Intestinal Inflammation and Altered Gut Microbiota Associated with Inflammatory Bowel Disease Render Mice Susceptible to Clostridioides difficile Colonization and Infection

Clostridioides difficile is a noteworthy pathogen in patients with inflammatory bowel disease (IBD). Patients with IBD who develop concurrent C. difficile infection (CDI) experience increased morbidity and mortality. IBD is associated with intestinal inflammation and alterations of the gut microbiot...

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Detalles Bibliográficos
Autores principales: Abernathy-Close, Lisa, Barron, Madeline R., George, James M., Dieterle, Michael G., Vendrov, Kimberly C., Bergin, Ingrid L., Young, Vincent B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262858/
https://www.ncbi.nlm.nih.gov/pubmed/34126769
http://dx.doi.org/10.1128/mBio.02733-20