Cleavage and Polyadenylation Specificity Factor 6 Is Required for Efficient HIV-1 Latency Reversal

The HIV-1 latent reservoir is the major barrier to an HIV cure. Due to low levels or lack of transcriptional activity, HIV-1 latent proviruses in vivo are not easily detectable and cannot be targeted by either natural immune mechanisms or molecular therapies based on protein expression. To target th...

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Detalles Bibliográficos
Autores principales: Zheng, Yue, Schubert, Heidi L., Singh, Parmit K., Martins, Laura J., Engelman, Alan N., D’Orso, Iván, Hill, Christopher P., Planelles, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262898/
https://www.ncbi.nlm.nih.gov/pubmed/34154414
http://dx.doi.org/10.1128/mBio.01098-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262898/
https://www.ncbi.nlm.nih.gov/pubmed/34154414
http://dx.doi.org/10.1128/mBio.01098-21

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