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Analysis of the Oxidative Stress Regulon Identifies soxS as a Genetic Target for Resistance Reversal in Multidrug-Resistant Klebsiella pneumoniae

In bacteria, the defense system deployed to counter oxidative stress is orchestrated by three transcriptional factors, SoxS, SoxR, and OxyR. Although the regulon that these factors control is known in many bacteria, similar data are not available for Klebsiella pneumoniae. To address this data gap,...

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Detalles Bibliográficos
Autores principales: Anes, João, Dever, Katherine, Eshwar, Athmanya, Nguyen, Scott, Cao, Yu, Sivasankaran, Sathesh K., Sakalauskaitė, Sandra, Lehner, Angelika, Devineau, Stéphanie, Daugelavičius, Rimantas, Stephan, Roger, Fanning, Séamus, Srikumar, Shabarinath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262902/
https://www.ncbi.nlm.nih.gov/pubmed/34098732
http://dx.doi.org/10.1128/mBio.00867-21