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Caspase-Dependent Cleavage of DDX21 Suppresses Host Innate Immunity

DEAD (Glu-Asp-Ala-Glu) box RNA helicases have been proven to contribute to antiviral innate immunity. The DDX21 RNA helicase was identified as a nuclear protein involved in rRNA processing and RNA unwinding. DDX21 was also proven to be the scaffold protein in the complex of DDX1-DDX21-DHX36, which s...

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Detalles Bibliográficos
Autores principales: Wu, Wei, Qu, Yang, Yu, Shengqing, Wang, Sa, Yin, Yuncong, Liu, Qinfang, Meng, Chunchun, Liao, Ying, Ur Rehman, Zaib, Tan, Lei, Song, Cuiping, Qiu, Xusheng, Liu, Weiwei, Ding, Chan, Sun, Yingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262918/
https://www.ncbi.nlm.nih.gov/pubmed/34125604
http://dx.doi.org/10.1128/mBio.01005-21