The SARS-CoV-2 Transcriptome and the Dynamics of the S Gene Furin Cleavage Site in Primary Human Airway Epithelia

The spike (S) polypeptide of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) consists of the S1 and S2 subunits and is processed by cellular proteases at the S1/S2 boundary that contains a furin cleavage site (FCS), (682)RRAR↓S(686). Various deletions surrounding the FCS have been ident...

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Detalles Bibliográficos
Autores principales: Zou, Wei, Xiong, Min, Hao, Siyuan, Zhang, Elizabeth Yan, Baumlin, Nathalie, Kim, Michael D., Salathe, Matthias, Yan, Ziying, Qiu, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262919/
https://www.ncbi.nlm.nih.gov/pubmed/33975939
http://dx.doi.org/10.1128/mBio.01006-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262919/
https://www.ncbi.nlm.nih.gov/pubmed/33975939
http://dx.doi.org/10.1128/mBio.01006-21

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