Cargando…

An Autocrine Negative Feedback Loop Inhibits Dictyostelium discoideum Proliferation through Pathways Including IP3/Ca(2+)

Little is known about how eukaryotic cells can sense their number or spatial density and stop proliferating when the local density reaches a set value. We previously found that Dictyostelium discoideum accumulates extracellular polyphosphate to inhibit its proliferation, and this requires the G prot...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Yu, Rijal, Ramesh, Zimmerhanzel, David E., McCullough, Jacquelyn R., Cadena, Louis A., Gomer, Richard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262924/
https://www.ncbi.nlm.nih.gov/pubmed/34154396
http://dx.doi.org/10.1128/mBio.01347-21