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Mix-and-Match System for the Enzymatic Synthesis of Enantiopure Glycerol-3-Phosphate-Containing Capsule Polymer Backbones from Actinobacillus pleuropneumoniae, Neisseria meningitidis, and Bibersteinia trehalosi

Capsule polymers are crucial virulence factors of pathogenic bacteria and are used as antigens in glycoconjugate vaccine formulations. Some Gram-negative pathogens express poly(glycosylglycerol phosphate) capsule polymers that resemble Gram-positive wall teichoic acids and are synthesized by TagF-li...

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Detalles Bibliográficos
Autores principales: Litschko, Christa, Budde, Insa, Berger, Monika, Bethe, Andrea, Schulze, Julia, Alcala Orozco, E. Alberto, Mahour, Reza, Goettig, Peter, Führing, Jana Indra, Rexer, Thomas, Gerardy-Schahn, Rita, Schubert, Mario, Fiebig, Timm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262930/
https://www.ncbi.nlm.nih.gov/pubmed/34076489
http://dx.doi.org/10.1128/mBio.00897-21