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Linking a Gene Cluster to Atranorin, a Major Cortical Substance of Lichens, through Genetic Dereplication and Heterologous Expression

The depside and depsidone series compounds of polyketide origin accumulate in the cortical or medullary layers of lichen thalli. Despite the taxonomic and ecological significance of lichen chemistry and its pharmaceutical potentials, there has been no single piece of genetic evidence linking biosynt...

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Detalles Bibliográficos
Autores principales: Kim, Wonyong, Liu, Rundong, Woo, Sunmin, Kang, Kyo Bin, Park, Hyun, Yu, Young Hyun, Ha, Hyung-Ho, Oh, Seung-Yoon, Yang, Ji Ho, Kim, Hangun, Yun, Sung-Hwan, Hur, Jae-Seoun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262933/
https://www.ncbi.nlm.nih.gov/pubmed/34154413
http://dx.doi.org/10.1128/mBio.01111-21