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Deacylated tRNA Accumulation Is a Trigger for Bacterial Antibiotic Persistence Independent of the Stringent Response

Bacterial antibiotic persistence occurs when bacteria are treated with an antibiotic and the majority of the population rapidly dies off, but a small subpopulation enters into a dormant, persistent state and evades death. Diverse pathways leading to nucleoside triphosphate (NTP) depletion and restri...

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Detalles Bibliográficos
Autores principales: Wood, Whitney N., Mohler, Kyle, Rinehart, Jesse, Ibba, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262941/
https://www.ncbi.nlm.nih.gov/pubmed/34126764
http://dx.doi.org/10.1128/mBio.01132-21