Circadian Clock Control of Translation Initiation Factor eIF2α Activity Requires eIF2γ-Dependent Recruitment of Rhythmic PPP-1 Phosphatase in Neurospora crassa

The circadian clock controls the phosphorylation and activity of eukaryotic translation initiation factor 2α (eIF2α). In Neurospora crassa, the clock drives a daytime peak in the activity of the eIF2α kinase CPC-3, the homolog of yeast and mammalian GCN2 kinase. This leads to increased levels of pho...

Descripción completa

Detalles Bibliográficos
Autores principales: Ding, Zhaolan, Lamb, Teresa M., Boukhris, Ahmad, Porter, Rachel, Bell-Pedersen, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262944/
https://www.ncbi.nlm.nih.gov/pubmed/34006661
http://dx.doi.org/10.1128/mBio.00871-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262944/
https://www.ncbi.nlm.nih.gov/pubmed/34006661
http://dx.doi.org/10.1128/mBio.00871-21

Ejemplares similares