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Parasite-Mediated Remodeling of the Host Microfilament Cytoskeleton Enables Rapid Egress of Trypanosoma cruzi following Membrane Rupture

Chagas’ disease arises as a direct consequence of the lytic cycle of Trypanosoma cruzi in the mammalian host. While invasion is well studied for this pathogen, study of egress has been largely neglected. Here, we provide the first description of T. cruzi egress documenting a coordinated mechanism by...

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Detalles Bibliográficos
Autores principales: Ferreira, Eden R., Bonfim-Melo, Alexis, Burleigh, Barbara A., Costales, Jaime A., Tyler, Kevin M., Mortara, Renato A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262949/
https://www.ncbi.nlm.nih.gov/pubmed/34154418
http://dx.doi.org/10.1128/mBio.00988-21