Phase Variation in HMW1A Controls a Phenotypic Switch in Haemophilus influenzae Associated with Pathoadaptation during Persistent Infection

Genetic variants arising from within-patient evolution shed light on bacterial adaptation during chronic infection. Contingency loci generate high levels of genetic variation in bacterial genomes, enabling adaptation to the stringent selective pressures exerted by the host. A significant gap in our...

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Detalles Bibliográficos
Autores principales: Fernández-Calvet, Ariadna, Euba, Begoña, Gil-Campillo, Celia, Catalan-Moreno, Arancha, Moleres, Javier, Martí, Sara, Merlos, Alexandra, Langereis, Jeroen D., García-del Portillo, Francisco, Bakaletz, Lauren O., Ehrlich, Garth D., Porsch, Eric A., Menéndez, Margarita, Mell, Joshua C., Toledo-Arana, Alejandro, Garmendia, Junkal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262952/
https://www.ncbi.nlm.nih.gov/pubmed/34154422
http://dx.doi.org/10.1128/mBio.00789-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262952/
https://www.ncbi.nlm.nih.gov/pubmed/34154422
http://dx.doi.org/10.1128/mBio.00789-21

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