Analysis of the Evolution of Pandemic Influenza A(H1N1) Virus Neuraminidase Reveals Entanglement of Different Phenotypic Characteristics

The influenza A virus (IAV) neuraminidase (NA) is essential for virion release from cells and decoy receptors and an important target of antiviral drugs and antibodies. Adaptation to a new host sialome and escape from the host immune system are forces driving the selection of mutations in the NA gen...

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Detalles Bibliográficos
Autores principales: Dai, Meiling, Du, Wenjuan, Martínez-Romero, Carles, Leenders, Tim, Wennekes, Tom, Rimmelzwaan, Guus F., van Kuppeveld, Frank J. M., Fouchier, Ron A. M., Garcia-Sastre, Adolfo, de Vries, Erik, de Haan, Cornelis A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262965/
https://www.ncbi.nlm.nih.gov/pubmed/33975931
http://dx.doi.org/10.1128/mBio.00287-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262965/
https://www.ncbi.nlm.nih.gov/pubmed/33975931
http://dx.doi.org/10.1128/mBio.00287-21

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