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Analysis of the Evolution of Pandemic Influenza A(H1N1) Virus Neuraminidase Reveals Entanglement of Different Phenotypic Characteristics
The influenza A virus (IAV) neuraminidase (NA) is essential for virion release from cells and decoy receptors and an important target of antiviral drugs and antibodies. Adaptation to a new host sialome and escape from the host immune system are forces driving the selection of mutations in the NA gen...
Autores principales: | Dai, Meiling, Du, Wenjuan, Martínez-Romero, Carles, Leenders, Tim, Wennekes, Tom, Rimmelzwaan, Guus F., van Kuppeveld, Frank J. M., Fouchier, Ron A. M., Garcia-Sastre, Adolfo, de Vries, Erik, de Haan, Cornelis A. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262965/ https://www.ncbi.nlm.nih.gov/pubmed/33975931 http://dx.doi.org/10.1128/mBio.00287-21 |
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