A Dual-Specificity Inhibitor Targets Polyphosphate Kinase 1 and 2 Enzymes To Attenuate Virulence of Pseudomonas aeruginosa

The opportunistic pathogen Pseudomonas aeruginosa is a leading cause of nosocomial infections, which are becoming increasingly difficult to treat due to antibiotic resistance. Polyphosphate (polyP) plays a key role in P. aeruginosa virulence, stress response, and antibiotic tolerance, suggesting an...

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Detalles Bibliográficos
Autores principales: Neville, Nolan, Roberge, Nathan, Ji, Xiang, Stephen, Preyesh, Lu, Jiasheng Louis, Jia, Zongchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262977/
https://www.ncbi.nlm.nih.gov/pubmed/34126765
http://dx.doi.org/10.1128/mBio.00592-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262977/
https://www.ncbi.nlm.nih.gov/pubmed/34126765
http://dx.doi.org/10.1128/mBio.00592-21

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