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The Carbapenemase BKC-1 from Klebsiella pneumoniae Is Adapted for Translocation by Both the Tat and Sec Translocons

The cell envelope of Gram-negative bacteria consists of two membranes surrounding the periplasm and peptidoglycan layer. β-Lactam antibiotics target the periplasmic penicillin-binding proteins that synthesize peptidoglycan, resulting in cell death. The primary means by which bacterial species resist...

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Detalles Bibliográficos
Autores principales: Bharathwaj, Manasa, Webb, Chaille T., Vadlamani, Grishma, Stubenrauch, Christopher J., Palmer, Tracy, Lithgow, Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262980/
https://www.ncbi.nlm.nih.gov/pubmed/34154411
http://dx.doi.org/10.1128/mBio.01302-21