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Annexin A1 restores cerebrovascular integrity concomitant with reduced amyloid-β and tau pathology

Alzheimer’s disease, characterized by brain deposits of amyloid-β plaques and neurofibrillary tangles, is also linked to neurovascular dysfunction and blood–brain barrier breakdown, affecting the passage of substances into and out of the brain. We hypothesized that treatment of neurovascular alterat...

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Detalles Bibliográficos
Autores principales: Ries, Miriam, Watts, Helena, Mota, Bibiana C, Lopez, Maria Yanez, Donat, Cornelius K, Baxan, Nicoleta, Pickering, James A, Chau, Tsz Wing, Semmler, Annika, Gurung, Brinda, Aleksynas, Robertas, Abelleira-Hervas, Laura, Iqbal, Soha Jamshed, Romero-Molina, Carmen, Hernandez-Mir, Gerard, d’Amati, Antonio, Reutelingsperger, Chris, Goldfinger, Marc H, Gentleman, Steve M, Van Leuven, Fred, Solito, Egle, Sastre, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8262982/
https://www.ncbi.nlm.nih.gov/pubmed/34148071
http://dx.doi.org/10.1093/brain/awab050