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An Egg-Derived Sulfated N-Acetyllactosamine Glycan Is an Antigenic Decoy of Influenza Virus Vaccines

Influenza viruses grown in eggs for the purposes of vaccine generation often acquire mutations during egg adaptation or possess different glycosylation patterns than viruses circulating among humans. Here, we report that seasonal influenza virus vaccines possess an egg-derived glycan that is an anti...

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Detalles Bibliográficos
Autores principales: Guthmiller, Jenna J., Utset, Henry A., Henry, Carole, Li, Lei, Zheng, Nai-Ying, Sun, Weina, Costa Vieira, Marcos, Zost, Seth, Huang, Min, Hensley, Scott E., Cobey, Sarah, Palese, Peter, Wilson, Patrick C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263001/
https://www.ncbi.nlm.nih.gov/pubmed/34126773
http://dx.doi.org/10.1128/mBio.00838-21