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A chimeric nuclease substitutes a phage CRISPR-Cas system to provide sequence-specific immunity against subviral parasites

Mobile genetic elements, elements that can move horizontally between genomes, have profound effects on their host's fitness. The phage-inducible chromosomal island-like element (PLE) is a mobile element that integrates into the chromosome of Vibrio cholerae and parasitizes the bacteriophage ICP...

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Detalles Bibliográficos
Autores principales: Barth, Zachary K, Nguyen, Maria HT, Seed, Kimberley D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263062/
https://www.ncbi.nlm.nih.gov/pubmed/34232860
http://dx.doi.org/10.7554/eLife.68339