Tet1 regulates epigenetic remodeling of the pericentromeric heterochromatin and chromocenter organization in DNA hypomethylated cells

Pericentromeric heterochromatin (PCH), the constitutive heterochromatin of pericentromeric regions, plays crucial roles in various cellular events, such as cell division and DNA replication. PCH forms chromocenters in the interphase nucleus, and chromocenters cluster at the prophase of meiosis. Chro...

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Detalles Bibliográficos
Autores principales: Hagihara, Yota, Asada, Satoshi, Maeda, Takahiro, Nakano, Toru, Yamaguchi, Shinpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263065/
https://www.ncbi.nlm.nih.gov/pubmed/34166371
http://dx.doi.org/10.1371/journal.pgen.1009646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263065/
https://www.ncbi.nlm.nih.gov/pubmed/34166371
http://dx.doi.org/10.1371/journal.pgen.1009646

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