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Spironolactone Ameliorates Senescence and Calcification by Modulating Autophagy in Rat Tendon-Derived Stem Cells via the NF-κB/MAPK Pathway

Tendinopathy is a disabling musculoskeletal disease, the pathological process of which is tightly associated with inflammation. Spironolactone (SP) has been widely used as a diuretic in clinical practice. Recently, SP has shown anti-inflammatory features in several diseases. Tendon-derived stem cell...

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Detalles Bibliográficos
Autores principales: Xu, Kai, Lin, Changjian, Ma, Diana, Chen, Mengyao, Zhou, Xing, He, Yuzhe, Moqbel, Safwat Adel Abdo, Ma, Chiyuan, Wu, Lidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263237/
https://www.ncbi.nlm.nih.gov/pubmed/34306308
http://dx.doi.org/10.1155/2021/5519587