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Agonist and antagonist properties of an insect GABA-gated chloride channel (RDL) are influenced by heterologous expression conditions

Pentameric ligand-gated ion channels (pLGICs) activated by the inhibitory neurotransmitter γ-aminobutyric acid (GABA) are expressed widely in both vertebrate and invertebrate species. One of the best characterised insect GABA-gated chloride channels is RDL, an abbreviation of ‘resistance to dieldrin...

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Detalles Bibliográficos
Autores principales: Smelt, Charles L. C., Sanders, Victoria R., Puinean, Alin M., Lansdell, Stuart J., Goodchild, Jim, Millar, Neil S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263253/
https://www.ncbi.nlm.nih.gov/pubmed/34234379
http://dx.doi.org/10.1371/journal.pone.0254251