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RANKL expression in chondrocytes and its promotion by lymphotoxin-α in the course of cartilage destruction during rheumatoid arthritis

We investigated the expression and localization of the receptor activator nuclear factor κB ligand (RANKL) in cartilage from patients with rheumatoid arthritis (RA) of relevance to cartilage degeneration. We also examined the role of exogenous lymphotoxin (LT)-α on RANKL expression in human chondroc...

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Detalles Bibliográficos
Autores principales: Takeshita, Ayumu, Nishida, Keiichiro, Yoshida, Aki, Nasu, Yoshihisa, Nakahara, Ryuichi, Kaneda, Daisuke, Ohashi, Hideki, Ozaki, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263262/
https://www.ncbi.nlm.nih.gov/pubmed/34234380
http://dx.doi.org/10.1371/journal.pone.0254268