Functional diversity of PFKFB3 splice variants in glioblastomas

Tumor cells tend to metabolize glucose through aerobic glycolysis instead of oxidative phosphorylation in mitochondria. One of the rate limiting enzymes of glycolysis is 6-phosphofructo-1-kinase, which is allosterically activated by fructose 2,6-bisphosphate which in turn is produced by 6-phosphofru...

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Detalles Bibliográficos
Autores principales: Heydasch, Ulli, Kessler, Renate, Warnke, Jan-Peter, Eschrich, Klaus, Scholz, Nicole, Bigl, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263283/
https://www.ncbi.nlm.nih.gov/pubmed/34234350
http://dx.doi.org/10.1371/journal.pone.0241092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263283/
https://www.ncbi.nlm.nih.gov/pubmed/34234350
http://dx.doi.org/10.1371/journal.pone.0241092

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