α-Particle-induced DNA damage tracks in peripheral blood mononuclear cells of [(223)Ra]RaCl(2)-treated prostate cancer patients

PURPOSE: One therapy option for prostate cancer patients with bone metastases is the use of [(223)Ra]RaCl(2). The α-emitter (223)Ra creates DNA damage tracks along α-particle trajectories (α-tracks) in exposed cells that can be revealed by immunofluorescent staining of γ-H2AX+53BP1 DNA double-strand...

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Detalles Bibliográficos
Autores principales: Schumann, S., Eberlein, U., Lapa, C., Müller, J., Serfling, S., Lassmann, M., Scherthan, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263441/
https://www.ncbi.nlm.nih.gov/pubmed/33537837
http://dx.doi.org/10.1007/s00259-020-05170-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263441/
https://www.ncbi.nlm.nih.gov/pubmed/33537837
http://dx.doi.org/10.1007/s00259-020-05170-6

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