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Primed to die: an investigation of the genetic mechanisms underlying noise-induced hearing loss and cochlear damage in homozygous Foxo3-knockout mice

The prevalence of noise-induced hearing loss (NIHL) continues to increase, with limited therapies available for individuals with cochlear damage. We have previously established that the transcription factor FOXO3 is necessary to preserve outer hair cells (OHCs) and hearing thresholds up to two weeks...

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Detalles Bibliográficos
Autores principales: Beaulac, Holly J., Gilels, Felicia, Zhang, Jingyuan, Jeoung, Sarah, White, Patricia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263610/
https://www.ncbi.nlm.nih.gov/pubmed/34234110
http://dx.doi.org/10.1038/s41419-021-03972-6