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Primed to die: an investigation of the genetic mechanisms underlying noise-induced hearing loss and cochlear damage in homozygous Foxo3-knockout mice
The prevalence of noise-induced hearing loss (NIHL) continues to increase, with limited therapies available for individuals with cochlear damage. We have previously established that the transcription factor FOXO3 is necessary to preserve outer hair cells (OHCs) and hearing thresholds up to two weeks...
Autores principales: | Beaulac, Holly J., Gilels, Felicia, Zhang, Jingyuan, Jeoung, Sarah, White, Patricia M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263610/ https://www.ncbi.nlm.nih.gov/pubmed/34234110 http://dx.doi.org/10.1038/s41419-021-03972-6 |
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